Comparing the Effect of Stannous Fluoride Toothpaste with Placebo in Treating Dentinal Hypersensitivity
Keywords:
Toothpaste, Hypersensitivity, Placebo, FluorideAbstract
OBJECTIVES
This study aimed to compare the efficacy of stannous fluoride toothpaste versus placebo in treating dentinal hypersensitivity.
METHODOLOGY
This quasi-experimental study was conducted at the Department of Periodontology, Rehman Medical Institute (RMI), Peshawar from July 25, 2023, to January 25, 2024. The study included 176 patients aged 18-70 years with at least two hypersensitive teeth. Participants were randomly divided into two groups: the test group (stannous fluoride toothpaste) and the control group (placebo). Sensitivity was measured at baseline, 3 minutes after application, and 15 days post-application using the Schiff Cold Air Sensitivity Scale (SCASS). Oral hygiene measures, clinical attachment loss, and gingival recession were also recorded. Data were analyzed using independent t-tests and Chi-square tests.
RESULTS
The test group showed significant improvement in SCASS scores compared to the control group (93.2% vs. 12.5%, p<0.001). Participants who used toothbrushes had significantly better outcomes than those using miswak or never engaging in oral hygiene. Participants who brushed more frequently experienced improved sensitivity relief, as effective brushing helps distribute the active fluorides uniformly across the teeth.
CONCLUSION
Stannous fluoride toothpaste significantly reduces dentinal hypersensitivity compared to placebo, supporting its use as an effective treatment for DH.
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Bae JH, Kim YK, Myung SK. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta‐analysis. Journal of clinical periodontology. 2015;42(2):131-41.
Gillam D, Koyi B. Dentin hypersensitivity in clinical practice: JP Medical Ltd; 2020.
Moraschini V, da Costa LS, Dos Santos GO. Effectiveness for dentin hypersensitivity treatment of non-carious cervical lesions: a meta-analysis. Clinical oral investigations. 2018;22:617-31.
Yadav BK, Jain A, Rai A, Jain M. Dentine hypersensitivity: a review of its management strategies. Journal of International Oral Health. 2015;7(10):137.
Dam VV, Trinh HA, Dung DT, Hai TD. Advances in the management of dentin hypersensitivity: An updated review. The Open Dentistry Journal. 2022;16(1).
Hu M-L, Zheng G, Jiang R-D, Han J-M, Zhang Y-D, Lin H. The evaluation of the desensitization effect of a desensitizing agent and desensitizing toothpastes in vitro. Dental Materials Journal. 2020;39(5):855-61.
Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, et al. Evaluation of the efficacy of dentin hypersensitivity treatments—A systematic review and follow‐up analysis. Journal of oral rehabilitation. 2019;46(10):952-90.
Hines D, Xu S, Stranick M, Lavender S, Pilch S, Zhang Y-P, et al. Effect of a stannous fluoride toothpaste on dentinal hypersensitivity: In vitro and clinical evaluation. The Journal of the American Dental Association. 2019;150(4):S47-S59.
Doğan Ç, Yıldırım HS, Gürsoy H, Kuru L. Occlusion of dentinal tubules on periodontally involved teeth by dentifrice containing stannous fluoride and sodium fluoride. Journal of Oral Science. 2023;65(3):149-52.
Haraszthy VI, Raylae CC, Sreenivasan PK. Antimicrobial effects of a stannous fluoride toothpaste in distinct oral microenvironments. The Journal of the American Dental Association. 2019;150(4):S14-S24.
Takamizawa T, Tsujimoto A, Ishii R, Ujiie M, Kawazu M, Hidari T, et al. Laboratory evaluation of dentin tubule occlusion after use of dentifrices containing stannous fluoride. Journal of oral science. 2019;61(2):276-83.
Mahmoodi B. Protection, remineralisation and tubule occlusion of dentine by desensitising toothpastes: University of Southampton; 2020.
Fiorillo L, Cervino G, Herford AS, Laino L, Cicciù M. Stannous fluoride effects on enamel: A systematic review. Biomimetics. 2020;5(3):41.
Prete B, Barsoum F, Ouanounou A. Toothpaste in Dentistry: A Review. Oral Health Group. 2022.
Grover V, Kumar A, Jain A, Chatterjee A, Grover HS, Pandit N, et al. ISP good clinical practice recommendations for the management of dentin hypersensitivity. Journal of Indian Society of Periodontology. 2022;26(4):307-33.
Creeth J, Maclure R, Seong J, Gomez‐Pereira P, Budhawant C, Sufi F, et al. Three randomized studies of dentine hypersensitivity reduction after short‐term SnF2 toothpaste use. Journal of clinical periodontology. 2019;46(11):1105-15.
Mrinalini UB, Hegde MN, Bhat GS. An update on dentinal hypersensitivity-aetiology to management–a review. J Evol Med Dent Sci. 2021;10(37):3289-93.
Arua SO, Fadare A, Adamu V. The etiology and management of dentinal hypersensitivity. Orapuh Journal. 2021;2(2).
Bagaria A, Garg V, Kumar K. Oral Hygiene The Pulse of the Practice: DENTOMED PUBLICATION HOUSE; 2022.
Frese C, Wohlrab T, Sheng L, Kieser M, Krisam J, Wolff D. Clinical effect of stannous fluoride and amine fluoride containing oral hygiene products: A 4-year randomized controlled pilot study. Scientific Reports. 2019;9(1):7681
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